Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is reported that CoV can be found in the brain or cerebrospinal fluid. The pathobiology of these neuroinvasive viruses is still incompletely known, and it is therefore important to explore the impact of CoV infections on the nervous system. Here, we review the research into neurological complications in CoV infections and the possible mechanisms of damage to the nervous system
CoV infections can affect the nervous system, and it is currently believed that CoV in concert with host immune mechanisms may turn these infections into persistent infections that may lead to neurological diseases. Therefore, patients with CoV infections should be evaluated early for neurological symptoms, including headache, consciousness disorder, paresthesia, and other pathological signs. Timely analysis of cerebrospinal fluid and awareness and management of infection-related neurological complications are key to improving the prognosis of critically ill patients.
Reference & Source information: https://www.ncbi.nlm.nih.gov/
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